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doi: 10.1016/j.cell.2009.11.042

This reduces EP2/EP4 receptor signaling, downregulates COX-2 and MMP-9 expression, and suppresses epithelial-mesenchymal transition (EMT), collectively reducing stromal cell invasion, migration, and proliferative expansion (Woo et al., 2021)

10.1093/carcin/bgt026 Carcinogenesis 86 SkrzypekK.TertilM.GoldaS.CieslaM.WeglarczykK.ColletG.et al (2013)

Rapamycin and the recently developed more specific mTOR inhibitors, i.e., rapalogs, are promising therapeutic compounds in the treatment of cancers and several autoimmune and chronic inflammatory diseases [66]