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( c ) Schematic of mouse model of chronic ethanol feeding plus acute binge (the NIAAA model) and its pair-fed control model (Created with Biorender.com)

ABCC1 deficiency potentiated noise-induced hearing loss in mice by impairing cochlear antioxidant capacity

Methods: We identified three unrelated adults with spastic ataxia, youngonset parkinsonism, frontal dysexecutive syndrome respectively, who on genetic analysis were found to have mutation in the CCDC88C gene, confirming the diagnosis of SCA40

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Several Alzheimer's pathological conditions are reported to be closely interrelated to oxidative stress