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found in their study that in clear cell renal cell carcinoma (ccRCC) tumor cells, endogenous Gln metabolism might reduce the anti-tumor effectiveness of T cells by promoting the Treg cell response ( 2.1.4 Regulation of tumor cell redox homeostasis Gln regulates the redox status of cancer cells by influencing the production of mitochondrial ROS

A 16-month randomized, placebo-controlled phase II clinical trial evaluated the safety and efficacy of 300, 600, or 1,200 mg/day of coenzyme Q 10 in 80 people with early Parkinson's disease (65)

Increases glucose uptake Enhances fat oxidation Improves mitochondrial efficiency Supports stress-response signaling It may also influence gene expression and antioxidant pathways , helping cells adapt to metabolic stress

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Cell culture HepG2 cells (ATTC-HB-8065, lot no