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Minogue BM, Richardson SM, Zeef LA, Freemont AJ, Hoyland JA: Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes

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The relatively low discontinuation rate despite side effects affecting 39-44% of users underscores an important point: most adverse events are tolerable and manageable, not severe enough to warrant stopping therapy