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Given their cute aesthetic, it only makes sense that Hello Kitty and the rest of the Sanrio mascots are constantly seen in various beauty and health products

Acknowledgements The authors declare that no funds, grants, or other support were received during the preparation of this manuscript

Moreover, since the inception of this study, multiple metabolic mechanisms promoting drug resistance have been suggested for 5FU treatment, including changes in amino acid metabolism 69,70 , serine and glycine metabolism 71,72,73 and glycolysis 74,75 , corroborated within our study and independently validating our findings