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Other interactions include those with: BRD3 (remodels DNA nucleosomes), [18] [19] [20] BRD4 (binds acetylated lysine residues in DNA-associated histone to regulate gene accessibility), [18] FLI1 (a transcription factor that blocks erythroid differentiation), [21] [22] HDAC1 (a histone deacetylase), [23] LMO2 (regulator of erythrocyte development), [24] ZBTB16 (transcription factor regulating cell cycle progression), [25] TAL1 (a transcription factor), [26] FOG2 (a transcription factor regulator), [27] and GATA2 (Displacement of GATA2 by GATA1, i.e