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Currently, clinical trials are investigating efficacy of CB-839 treatment in AML (NCT02071927) ( 5 Conclusions Considering our results and those of previous studies, we suggest that CLL cells can efficiently rewire their amino-acid and glucose metabolism to evade glutaminase inhibition

Semin Immunopathol (2012) 34(5):64353.10.1007/s00281-012-0320-1 9 VickeryBPChinSBurksAW

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Pyruvate concentrations of the samples were calculated based on the absorbance of the standards

As a negative control, you may use Dynabeads Protein G magnetic beads or Dynabeads Protein A magnetic beads bound to an irrelevant IgG