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The emerging understanding of glycolysis, lactate metabolism and lactylation in tissue fibrosis reveals new avenues for research and therapeutic intervention (Fig

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HF6 group: fed for 6 weeks with the high fat - high fructose (HF) diet

To further confirm that the p62-Keap1-NRF2 axis is responsible for the high expression of GPX4 in EBV-infected cells, we examined the effect of NRF2 on GPX4 expression in EBV-negative and EBV-positive NPC cells using siRNAs against NRF2