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doi: 10.1158/1078-0432.CCR-22-0655

What a degraded product looks like: Discoloration (yellowish or cloudy solution that was previously clear), visible particulate matter, or unexpected viscosity change all suggest degradation or contamination

IgG-depleted serum (IgGDepleted) and pooled plasma used for intravenous immunoglobulin (IVIG) therapy were used as negative and positive controls, respectively