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A 2018 Cochrane review that included eight studies that focused on antioxidants, including beta carotene, found small benefits associated with beta carotene supplementation on cognitive function and memory

Rather, it's better to take these supplements on their own

1 2 "Advances in the understanding of cobalamin assimilation and metabolism"

It is not approved for human therapeutic use, and any research use should comply with applicable institutional and regulatory guidelines

The bloodbrain barrier tightly regulates brain extracellular composition of glutamine, glutamate and GABA irrespective of the level in the blood (Reference Hawkins and Vina46,Reference Dolgodilina, Imobersteg and Laczko47)