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IGF2BP3s role was validated through knockdown/overexpression, patient-derived organoids (PDOs), and xenograft models

Multi-target Joints, gut & tissue (preclinical)

doi: 10.1016/j.jchromb.2009.09.039

Such a balance between skin retention and permeation is particularly relevant in radiation-induced skin injury, where sustained local drug action is more desirable than systemic exposure

The term "pharmaceutically acceptable salts" refers to salts derived from various organic and inorganic counterions known in the art (see, e.g., Berge et al (1977) j.pharm.sci.66: 1-19)