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It has demonstrated low skin irritability when applied topically, both with and without microneedle-assisted delivery

This can lead to focusing on one condition while missing others, or to attributing all difficulties to a single diagnosis when multiple conditions may be present

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Acute BRVO presents characteristic clinical features with flame-shaped, dot and blot hemorrhage, soft and hard exudates, retinal edema, and dilated, tortuous vein in a segmental distribution