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doi: 10.1111/j.1742-4658.2006.05548.x 72 IslamT.MannaM.ReddyM

Furrie E, Macfarlane S, et al

doi:10.1016/j.mce.2011.06.015 111

Under the induction of oxidative stress, a part of HIF-1 is translocated to mitochondria, where it inhibits the respiratory chain by lowering the expression of mtDNA-encoded mRNA that responses to hypoxia, thus preventing the over-production of ROS and resisting oxidative stress