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Malabsorption (insufficient absorption of vitamin B 12 in the intestine) due to, insufficient production of intrinsic factor (a protein that is formed in the gastric mucosa and is required for the absorption of vitamin B 12 ), Diseases in the end section of the ileum (part of the small intestine), e.g.B

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Crohns Disease and Other GI Conditions B12 is absorbed in the terminal ileum (the last section of the small intestine)

Here, lower maintenance doses of 3-5 mg, three times per week, sustained over months and cycled appropriately, may be more aligned with the goal than high-frequency maximum doses

This study suggests that the CD38/cADPR signaling pathway plays a crucial role in epileptogenesis [59]