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Hepatic mitochondria provide a hub for liver metabolic homeostasis by uniquely integrating or coordinating multiple metabolic pathways of carbohydrate, lipid, cholesterol, bile acid, and amino acids for energy homeostasis and by keeping the balance of reducing equivalents and intermediary metabolites in the liver and whole body via mitochondria-cytoplasm shuttles

As this technology becomes more widespread, its integration into standard medical protocols appears inevitable

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