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Both initial and maintenance probings are intended to mechanically open Meibomian gland orifices and ducts, remove obstructions, maintain patency of orifices and ducts, restore gland function, increase oil production (qualitatively and quantitatively), and stabilize the tear film, thus relieving symptoms of Meibomian gland dysfunction, blepharitis, ocular rosacea, and dry eye

Reduced heart rate variability predicts poor sleep quality in a casecontrol study of chronic fatigue syndrome

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Its oral bioavailability in animal models (unusual for a peptide) has also generated interest in delivery route comparisons

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