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In the SURMOUNT-1 trial, tirzepatide at 15 mg achieved a mean weight reduction of 20.9%, approximately 6 percentage points above semaglutide's best result in comparable populations

The longevity of the results will vary depending on the patient, how quickly their skin degenerates with age, and the particular conditions treated

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After 28 days, the benzyl alcohol concentration may be insufficient to prevent microbial contamination

[22] The model corresponds to a pharmacokinetic single-compartment model with instantaneous absorption and zero-order kinetics for elimination