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There is evidence that the depletion of SOD, a mitochondrial free radical scavenger, in connective tissue leads to the acceleration of skin ageing [123]

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Conversely, mitigating oxidative stress specifically in HCs (via Gpx4 overexpression) reduced ERK phosphorylation in SCs, likely through EGFR signaling across the SC membrane, leading to GSDMD activation

suis strain HS5bLP, isolated from the gastric mucosa of a sow 55 , was used for experimental infection of Mongolian gerbils

Kim, B.-H