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Cited 6/24/2026

2022;23(22) doi: 10.3390/ijms232213850

Serial dilutions ( H

In tumor-microenvironment models such as glioma co-culture, mitochondrial membrane potential, enzymatic activity, and ATP synthesis decline, while extracellular lactate production increases, indicating a metabolic shift from oxidative phosphorylation toward aerobic glycolysis (217)