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Please consult your doctor regarding use in pregnant females

Methods 38 patients were included in a cross-sectional survey

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Exogenous administration of FGF21 in DIO in mice show virtually no beneficial effects on glucose tolerance and lipid metabolism, suggesting that the obesity state is FGF21-resistant (240)

Semaglutide is often preferred for patients with milder weight-loss goals or histories of severe GI side effects, because tirzepatide tends to produce stronger nausea during titration