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Also, low-concentration paclitaxel (2 nM) enhanced RSL3-induced ferroptosis by upregulating the expression of p53 variants Nanoformulations Nanoformulation using targeted nanoparticles such as dendrimers is an emerging strategy in cancer therapeutics

330 Another PRMT5 inhibitor, JNJ-64619178, has shown long-term PRMT5 inhibition and potent anti-tumor effect in lung, pancreatic, and hematological tumors

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Subsequently, the heterodimer (HIF-:HIF-) migrates to hypoxic response elements (HREs) of the target gene and activates the transcription of multiple genes involved in multiple cellular pathways (35)