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The disease usually progresses symmetrically (810)

They also release pro-inflammatory cytokines and growth factors, which mobilize additional immune cells and enhance keratinocyte, fibroblast, and epithelial cell proliferation observed during the proliferative and remodeling phases

These reasons likely account for the observed lower response to ESAs in the setting of acute illness and explain why ESAs are not recommended for correcting acute anemia

Certificate of Analysis Click here Storage & Handling Lyophilised storage: Keep at 20 C in a dry, desiccated environment After reconstitution: Store at 28 C and use within 30 days Long-term storage: Aliquot and freeze at 20 C where required Avoid repeated freezethaw cycles Reconstitution: Use sterile bacteriostatic water or a suitable laboratory buffer depending on research protocol For research use only