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Reduced glutathione metabolism can lead to oxidative stress associated with mitochondrial dysfunction, neuroinflammatory response and the neurodegenerative progression of Parkinsons disease

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It is also possible that with further validation 29 and possibly with appropriate management of multi-site issues 30,31 , brain GSH concentration response to NAC could be monitored using 3 T MRS, which is more widely available than 7 T MRS

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