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Glutathione-depleting pro-oxidant as a selective anticancer therapeutic agent

Myofibroblasts are known to arise from several sources, with resident fibroblasts and epithelial-to-mesenchymal transition (EMT/EndMT) being the primary contributors ( One of the main sources of myofibroblasts in fibrotic tissues is the activation of resident fibroblasts ( In addition to resident fibroblasts, myofibroblasts can also originate from epithelial and endothelial cells through a process termed EMT or EndMT, respectively ( The genesis of myofibroblasts is a complex and multifaceted process