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frondosa (3.88 gL 1 ) (Osiska-Jaroszuk et al

These drugs inhibited mutant IDH1 R132H in nanomolar range and exhibited promising selectivity over wild type IDH1

Many proteins tend to aggregate or form insoluble inclusion bodies when expressed in host cells like E

Sequencing analysis confirmed that the Sec and Cys codon(s) of hGPx3 gene was(were) changed to Cys and Ser codon(s), respectively and no undesired mutation was introduced during the cloning process