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Baclofen is available in various forms, including oral tablets and an intrathecal delivery system, which involves administering the drug directly into the spinal fluid

Participants then increase their dose gradually, usually every four weeks, until they reach the target dose being studied

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They also offer more controllable results, making them more ideal for precise enhancements like the lips, and PRF more suitable for broader areas, such as tear troughs

doi: 10.1590/1413-81232018236.06022018, 23