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Increased inactivation of cisplatin by thiol-containing proteins is an important mechanism for tumor resistance, as showed for cervical cancers, osteosarcoma and glioblastoma cells 4,14,15,28

In addition, the combination of luteolin and quercetin inhibits the - activity of hexosaminidase ( Persicaria perfoliata (L.) H

n = 211) from the GOOS cohort

Kornblau SM , Xu HJ, Smith TL, Beran M, Hester J, Benedict WF, Deisseroth AB

Superimposed on these functional alterations are large numbers of passenger mutations, which are largely neutral but serve as molecular records of evolutionary history (76, 77)