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Inositol tham gia vo nhiu qu trnh sinh hc quan trng

EpEX sheds outside the cell, and EPICD is released to the cytoplasm

doi: 10.1016/j.cell.2014.11.037 25 WhiteMJMcArthurKMetcalfDLaneRMCambierJCHeroldMJet al

Cancers 13 (3), 452 (2021)

These are studying different therapeutic approaches aiming (a) to reduce intramitochondrial oxidative stress (idebenone, coenzymeQ, vitamin E, iron chelators), (b) to enhance frataxin endogenous expression (erythropoietin, pioglitazone), or (c) to increase FRDA gene expression (HDAC inhibitors, interferon )