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When glutathione levels are low, oxidative stress and inflammation can build up and contribute to early signs of aging

Selinexor inhibits XPO1 and has been approved for the treatment of patients with relapsed/refractory multiple myeloma after one to three prior lines of therapy in combination with bortezomib or pomalidomide with dexamethasone, or after 3 prior lines with dexamethasone alone

The prescribing information recommends using a non-oral contraceptive method or adding a barrier method for 4 weeks after treatment initiation and for 4 weeks after each dose escalation

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