A more recent report revealed that bumetanide could reduce amygdala activation in adolescents with ASD, in which authors hypothesized that bumetanide restores the E-I balance of brain 19
Reddy SK, Husain K, Schlorff EC, Scott RB, Somani SM
Finally, personalized nursing plans that utilize these discoveries to individual patients, are discussed, thereby completing the mechanism-to-intervention cycle

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Semaphorin 3A is such a repulsive signal, detected by the plexin1/neuropilin receptor pair