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The kynurenine pathway: a finger in every pie

doi: 10.1016/j.conb.2021.03.003 91 WuD.ChenQ.ChenX.HanF.ChenZ.WangY

T.HoanN

This is particularly relevant given that, while AR inhibitors (e.g., epalrestat) are used to treat diabetic neuropathy in some countries, they have not yet been widely recognized as a definitive therapeutic approach worldwide ( Overall, our findings support the therapeutic potential of AR inhibitors as a targeted pharmacological strategy for polyol pathway-related neuropathies