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However, human experiments confirmed that only obese Chinese male children/adolescents (5-14 years old) had significantly lower (20.3%) intra-cycle MOTS-C levels (22)

The triggered signaling process leads to the expression of proinflammatory cytokine-inducing transcription factors, such as NF-kB, as well as to activate interferon regulatory factors that mediate the type I interferon-dependent antiviral response [17]

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