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This encompasses factors include internalization, recycling, turnover rates, lysosomal degradation, and obligate mechanisms [26]

Using this approach, we discovered a novel role for the melanogenesis-associated transcription factor, or MITF, in repressing the expression of innate immune genes within cells of the melanocyte lineage in mice. The importance of this repression is revealed in animals that have a predisposition for hair-graying

It reduces inflammatory cell recruitment, contributes to hormonal regulation, interferes with chemokine-mediated lesion establishment, and modulates mitochondrial biogenesis in a context-dependent manner

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