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The advantage of using diquat to induce oxidative stress is the accumulation of diquat in the kidneys and liver relatively than paraquat, which occurs in the lungs

149 Bioinformatic analysis and immunohistochemical results of clinical samples show that KLF2 expression is reduced in patients with metastatic RCC, and overall survival and metastasis-free survival are shortened in patients with low KLF2 expression

They also recommended expanding genotyping panels to include other relevant pharmacokinetic and pharmacodynamic genes beyond CYP2D6 and CYP2C19 , thereby capturing the full scope of genetic determinants influencing antidepressant response

Zanotto-Filho A, Braganhol E, Klafke K, Figueir F, Terra SR, Paludo FJ, Morrone M, Bristot IJ, Battastini AM, Forcelini CM, Bishop AJR, Gelain DP, Moreira JCF