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Am J Respir Crit Care Med 186:857865

The researchers observed significant and consistent increases in neuronal activity just minutes following intranasal administration, finding that at least the first peak of activity was linked to epithalons direct action on cortical cells [3]

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In -synuclein-induced PD mouse model, Zhang and collaborators showed that the administration of caffeic acid prevents the neurodegeneration of dopaminergic neurons in SN and improves behavioral abnormalities by stimulating autophagy through the JNK/BcL2 pathway (Zhang et al., 2019)