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PMID: 42313564 Cell Rep Intralaminar thalamus relays basal ganglia output to the insular cortex to drive tic generation

Clinical Trial Study Environment Clinical and HF studies have distinct goals and environments

Confirmation of a direct role for GSTP1 in chemotherapy response is important, not only in the prediction of response to platinum-based chemotherapy, but as a candidate response biomarker for new generation chemotherapy drugs, designed to exploit increased GSTP1 expression in tumours relative to surrounding normal tissues

Epigenetic changes, such as DNA methylation and histone modification, can regulate gene expression in response to mechanical stress

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