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A structural mechanism for directing corepressor-selective inverse agonism of PPAR

As described above, we used mutants of hTrxR1 (hTrxR1 C497S,U498C ) and hTrx1 (hTrx1 C35S,C73S ) to obtain crystals of the reaction intermediate between hTrxR1 and hTrx1

517 Within the C-terminal region, ZnT8A can specifically target amino acid 325 of ZnT8, and this specificity is determined by the SLC30A8 polymorphism rs13266634

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