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It is important to acknowledge that this analysis is purely predictive, and although based on validated and well established bioinformatic pipelines, it is intended solely to provide insights into the metabolic potential based on the genetic potential explored via the metagenomic analysis

Chronic Candida overgrowth progressively depletes secretory IgA (sIgA), the guts primary antibody defence, creating a vicious cycle in which reduced immune surveillance allows further yeast proliferation and biofilm formation

Altered metabolic activity of the purine cycle has been linked with several MDD-related systemic responses, such as increased proinflammatory and oxidative processes 35