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While the evidence for EPO is less robust than for some other supplements on this list, it has a long history of use, a reasonable safety profile, and many women find it helpful for breast tenderness and mood symptoms specifically

It works more like a B vitamin than a typical amino acid

Supports fat burn + workout performance

Therefore, the review suggests that, to improve FM symptoms, physical exercise and an energy deficit are necessary, as elevated BMI levels have been directly linked to increased pain and functional status in FM patients [28]

AEP-C is funded by a Grant for the Attraction of Talent within the Community of Madrid (2019-T2/BMD-12874)