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Studies have shown that excessive HOCl/OH generation during neutrophil activation induces extensive DNA damage and subsequent DNA repair mechanisms which will result in NETosis [246, 247]

Dispose of sharps directly into the sharps bin and dispose of the syringe according to local policy

In other studies, shikonin and its analogues have been reported to have insecticidal activities toward Culex pipiens (Michaelakis, et al., 2009), Tetranychus urticae (Stefania, et al., 2017), and Nilaparvata lugens (Shang et al., 2019)