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doi: 10.1007/s10549-011-1624-x 61 MarinYEChenS

Berberine Attenuates Intracranial Aneurysm Formation by Activating SIRT1 to Suppress HMGB1 Acetylation and NF-B Signaling

Its activity decreases in alkaline pH

Vascular endothelial growth factor (VEGF) is both a major angiogenic factor and one of the osteogenic growth factors, significantly contributing to maintaining skeletal structure and promoting bone formation [9]