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The platform uses hydrophilic interaction liquid chromatography with positive/negative ion switching to analyze 258 metabolites (289 Q1/Q3 transitions) from a single 15-min targeted liquid chromatographytandem mass spectrometry (LCMS/MS) acquisition with a 3-ms dwell time and a 1.55-s duty cycle time (Yuan et al

These include drugs like: Semaglutide (commonly known as Ozempic or Wegovy) Tirzepatide (Mounjaro or Zepbound) These are usually taken as weekly injections

In rabbits administered tirzepatide during organogenesis, fetal growth reductions were observed at clinically relevant exposures based on AUC

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However, insulin significantly increased basal oxygen consumption rate (OCR