When administered in a liquid form, you can apply 1cc-3 cc to 1 oz to a gallon of water per day, although this will vary based on the animal
NICE Clinical Knowledge Summaries recommend B12 injections for: Pernicious anaemia an autoimmune condition affecting intrinsic factor production Malabsorption syndromes including coeliac disease and inflammatory bowel disease Post-surgical states particularly following gastrectomy or ileal resection Strict vegan diets when oral supplementation proves inadequate, though oral cyanocobalamin is usually sufficient for dietary deficiency Clinical trials demonstrate that B12 injections rapidly improve haematological parameters and neurological symptoms when deficiency is confirmed through blood tests
While most people can benefit from a B12 injection, certain groups of people may see more obvious benefits than others: People With Signs Of B12 Deficiency Any person with the signs or symptoms of a B12 deficiency should pay a visit to their doctor, but an injection may still provide them with benefits
Clin Auton Res 29:363366 Fanciulli A, Gobel G, Ndayisaba JP, Granata R, Duerr S, Strano S, Colosimo C, Poewe W, Pontieri FE, Wenning GK (2016) Supine hypertension in Parkinsons disease and multiple system atrophy
Somewhat unexpectedly, this animal model closely resembles children and adolescents with type 1 diabetes, as further elaborated on below