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found that EGCG has prophylactic effects on lupus nephritis in these mice that are highly associated with its effects of enhancing the Nrf2 antioxidant signaling pathway, decreasing renal NLRP3 inflammasome activation, and increasing systemic Treg cell activity [22, 25]

doi: 10.1016/J.IJBIOMAC.2023.126049 154 SamS.JosephB.ThomasS

Moreover, HR instigates the systemic signals that stimulate the defence-linked responses in distal plant tissues, resulting in systemic acquired resistance (SAR)

Ruixin L, Cheng X, Yingjie L, Hao L, Caihong S, Weihua S

As described previously, GSTs are known to clear intracellular ROS and assist in redox balance regulation (38)