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Similar content being viewed by others Background From the ancient aphoristic sagacity of Hippocrates, stating all diseases begin in the gut, to the modern medical research emphasising the importance of the gut in various aspects of human health, the intestinal microbiome has always played an essential role in the understanding of the healthy functioning of the human body [1, 2]

doi: 10.1016/j.jhin.2011.09.003 311 KhodaiiZAfrasiabiSHashemiSAArdeshirylajimiANatanziMM

The authors demonstrated that inhibition of acetylation of Mfn2 by sirtuin or overexpression of Mfn2 reduced mitochondrial fragmentation and enhanced the removal of damaged mitochondria (Alka et al., 2023)

Leslie Squier [psychology 195388] advising

They formulated the hypothesis that this pathway would be an alternative to glycolysis and is involved in cellular respiration