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In aged skeletal muscle models, NNMT inhibitor treatment increased proliferating/active muscle stem cells by 60-75% following injury, myofiber cross-sectional area increased 1.8-fold at one week post-injury with high-dose treatment, and peak torque of injured muscle increased by 67% compared to control (p = 0.033), with no untoward systemic toxicity observed in plasma chemistry markers (Neelakantan et al., 2019)

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Vegans (people who dont consume any meat products) and people lacking intrinsic factors are at risk of vitamin B12 deficiency

Actual timing depends on hydration status, sleep, stress, nutrition, and individual response

A commenter expressed concern about the 65-day timeline for patients to respond to the survey