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This resulted in the selection of leucovorin and dyclonine, two FDA-approved compounds, which we demonstrated to have brain repair and pro-oligodendrogenic activities in both preterm birth brain injury and adult demyelination mouse models, with leucovorin demonstrating broader beneficial effects

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Changes in glutamine and glutamate levels between people with AMD and controls, as well as between different AMD severity stages, can be linked to problems with the neurotransmitter supply that is crucial for the retina and visual pathway (Lains et al., 2018)