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Folic Acid (1.5 mg): Essential for DNA synthesis, cell division, and red blood cell production

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S2CID 41163109

[5] Hypertension presents a risk for intracranial hemorrhage (i.e., bleeding in the brain) and, if severe, is typically treated with intravenous phentolamine or nitroprusside

While genetic knockout substrains show genotypic and phenotypic pathways for mitigating loss of a target gene (ie., evolved similar phenotypes or secondary mutations in off-target genes), gene overexpression is perhaps more complicated in that the amount of target protein expression is highly variable, alongside the possible genome-wide effects of the mutation