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In neurology, CP functions as a second- or third-line immunosuppressant for severe neuroimmunological disorders, especially when first-line therapies have proven ineffective

Mechanistically, these effects appeared to be mediated through mitochondrial uncoupling, AMPK activation, modulation of mTOR and PPAR signaling, improved mitochondrial bioenergetics, antioxidant defense and global metabolic reprogramming (Fig