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This reversal was seen also on the background of the disturbed prostaglandins- and NO-systems, prostaglandins synthesis inhibition as well as NO-overstimulation (NOS-substrate L-arginine) or NO-blockade (N(G)-nitro-L-arginine methyl ester (L-NAME)) (Stupnisek et al., 2012

That does not mean BPC-157 has no role around painful joints

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Keep the tubes at 28C, away from light, and use them before the expiry date for reliable results